| Player | Pos | Seasons | Born | Birthplace | |
| Frank LaCorte | P | 1979-83 | Oct 13, 1951 | San Jose | CA |
| Mike LaCoss | P | 1982-84 | May 30, 1956 | Glendale | CA |
| Pete Ladd | P | 1979 | Jul 17, 1956 | Portland | ME |
| Brandon Laird | 1B/3B/DH | 2012-13 | Sep 11, 1987 | Cypress | CA |
| Jack Lamabe | P | 1965 | Oct 3, 1936 | Farmingdale | NY |
| Mike Lamb | 3B/1B | 2004-07 | Aug 9, 1975 | West Covina | CA |
| Keith Lampard | OF | 1969-70 | Dec 20, 1945 | Warrington | UK |
| Rafael Landestoy | 2B/SS | 1978-81 | May 28, 1953 | Bani | DR |
| Jim Landis | OF | 1967 | Mar 9, 1934 | Fresno | CA |
| Jason Lane | OF | 2002-07 | Dec 22, 1976 | Santa Rosa | CA |
| Norm Larker | 1B | 1962 | Dec 27, 1930 | Beaver Meadows | PA |
| Don Larsen | P | 1964-65 | Aug 7, 1929 | Michigan City | IN |
| Dan Larson | P | 1976-77 | Jul 4, 1954 | Los Angeles | CA |
| Barry Latman | P | 1966-67 | May 21, 1936 | Los Angeles | CA |
| Wade LeBlanc | P | 2013 | Aug 7, 1984 | Lake Charles | LA |
| Carlos Lee | OF/1B | 2007-12 | Jun 20, 1976 | Aguadulce | PN |
| Don Lee | P | 1965-66 | Feb 26, 1934 | Globe | AZ |
| Denny Lemaster | P | 1968-71 | Feb 25, 1939 | Corona | CA |
| Mark Lemongello | P | 1976-78 | Jul 21, 1955 | Jersey City | NJ |
| Jeff Leonard | OF | 1978-81 | Sep 22, 1955 | Philadelphia | PA |
| Brad Lidge | P | 2002-07 | Dec 23, 1976 | Sacramento | CA |
| Bob Lillis | SS/2B | 1962-67 | Jun 2, 1930 | Altadena | CA |
| José Lima | P | 1997-2001 | Sep 30, 1972 | Santiago | DR |
| Jim Lindeman | 1B | 1993 | Jan 10, 1962 | Evanston | IL |
| Matt Lindstrom | P | 2010 | Feb 11, 1980 | Rexburg | ID |
| Scott Linebrink | P | 2000-03 | Aug 4, 1976 | Austin | TX |
| Francisco Liriano | P | 2017 | Oct 26, 1983 | San Cristobal | DR |
| Pat Listach | SS/OF | 1997 | Sep 12, 1967 | Natchitoches | LA |
| Chia-Jen Lo | P | 2013 | Apr 7, 1986 | Pingtung County | TW |
| Kenny Lofton | OF | 1991 | May 31, 1967 | East Chicago | IN |
| Steve Lombardozzi | 2B | 1989-90 | Apr 26, 1960 | Malden | MA |
| Davey Lopes | OF/3B | 1986-87 | May 3, 1945 | East Providence | RI |
| Aurelio López | P | 1986-87 | Sep 21, 1948 | Tecamachalco | MX |
| Mendy López | 2B/3B | 2001 | Oct 15, 1973 | Pimentel | DR |
| Wilton López | P | 2009-12 | Jul 19, 1983 | Leon | NI |
| Mark Loretta | 2B/SS/3B/1B | 2002, 2007-08 | Aug 14, 1971 | Santa Monica | CA |
| Scott Loucks | OF | 1980-83 | Nov 11, 1956 | Anchorage | AK |
| Jed Lowrie | SS/3B | 2012, 2015 | Apr 17, 1984 | Salem | OR |
| Julio Lugo | SS/2B | 2000-03 | Nov 16, 1975 | Barahona | DR |
| Jordan Lyles | P | 2011-13 | Oct 19, 1990 | Hartsville | SC |
| Brandon Lyon | P | 2010-12 | Aug 10, 1979 | Salt Lake City | UT |